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Beilstein J. Org. Chem. 2015, 11, 2125–2131, doi:10.3762/bjoc.11.229
Graphical Abstract
Scheme 1: The synthesis of pyrazolo[3,4-d]pyrimidines.
Figure 1: Four-component one-pot synthesis of 5. Reactions conditions: 1 (1.2 mmol), 2 (1.0 mmol), 3 (1.2 mmo...
Scheme 2: Synthesis of 5a from different intermediates.
Scheme 3: Possible reaction mechanisms for the formation of pyrazolo[3,4-d]pyrimidiine.
Figure 2: Molecular structure (from X-ray diffraction data) of 5g.